Ant McPartlin and Declan Donnelly have been rumbled by fans as the reason for Lorraine's bizarre chat with rapper KSI on Monday.
Viewers of the morning show flocked to Twitter to debate Lorraine's bizarre 10 minute interview.
During the short segment she complained she had cramp, got up out of her chair to look for a mouse, and kept swatting away a fly.
Halting the interview, Lorraine told KSI: "Oh darling I'm sorry.. I got cramp in my leg
"Ah sorry it's really annoying. It's poppycock that is what it is."
Lorraine also repeatedly told KSI that she really wanted to see him in person.
At the end of the episode she hinted something was up by telling viewers: "It's been a very strange day – all will be revealed."
While unconfirmed, fans are convinced Ant and Dec have signed Lorraine up for the latest edition of Saturday Night Takeaway skit Get Out My Ear.
The segment sees a celeb wear a tiny earpiece to allow Ant and Dec to give them instructions of what to say and how to act.
Kate Garraway's husband Derek Draper told Good Morning Britain host he 'couldn't go on'
Previous star who have taken part include Cheryl and Harry and Jamie Redknapp.
The Masked Singer judge Davina McCall has also got involved in the hilarious segment in the past too.
As Lorraine's interview played out, one fan wrote: "What happened to Lorraine this morning? Is she ok? That was the weirdest thing to watch this morning."
Another added: "Lorraine strange lol.
Lorraine descends into chaos as mouse invades studio and host yawns during bizarre chat
"I think she was under the influence of Ant and Dec lol (well I hope so – or she is in need of medical attention lol)."
A third chimed in: "I think Lorraine is doing Ant and Dec she said all will be revealed lol."
A fourth guessed: "Definitely something fishy going on. Maybe Ant and Dec for Saturday Night Takeaway?"
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